Neurologist
Recommended
Made in
Canada
Convenient
Dosing
Stop migraine before it starts.
Health Canada
Simple supplement regimen to help prevent acute migraine attacks.
Why is 
the magic number?
Our innovative 3graine formula combines three neurologist-recommended ingredients and their dosages into a single daily serving of only three capsules to help with the treatment of migraine attacks. 3graine helps relieve headache pain with a convenient, preventative treatment all in one product.
Our migraine pain-relieving supplement helps stop migraine attacks before they start.
We know migraine pain and the frustration of dealing with a migraine headache personally. We have developed a migraine prevention supplement that helps prevent your headache pain and migraine symptoms before they start.
The 3 Ingredients
400mg
Vitamin B2 (Riboflavin)
High doses of vitamin B2 can help reduce oxidative stress and maintain a healthy level of mitochondrial reserves in those with migraine.
300mg
Magnesium (Citrate)
Important in managing migraine as it modules neuronal excitability and supports proper
nerve function.
200mg
Coenzyme Q10
An antioxidant that supports mitochondrial energy production, which may be impaired in individuals with migraine.
Neurologist Recommended
By reviewing the research and existing migraine supplements, we worked with Canadian Neurologists to develop this novel Canadian migraine supplement. We then formulated the optimal preventative supplement for migraine prevention.
Made in Canada
Physician-tested and authorized for sale by Health Canada, our quality migraine pain relief supplement helps prevent migraine symptoms before they start.
Convenient Dosing
When you’re dealing with chronic migraine symptoms, you don’t want pain-relieving supplements that require you to figure out
the dosages. We have created a 3-in-1 supplement to help reduce migraine pain.
How 
helps with migraine relief.
helps with migraine relief. Simple supplement regimen to help prevent acute migraine attacks. Developed based on clinical experience and scientific research on headache management.
When taken daily for at least 3 months, 
may provide the following benefits:
may provide the following -
Decrease the severity of headaches -
Decreases frequency of headaches -
Decrease nausea & vomiting associated with migraine
We set out to help
make headache
support more convenient.
Too many pills?
Too many products?
Too many dosages?
As healthcare practitioners, we saw firsthand that our patients had a hard time starting and maintaining their headache supplement regimen.
So we made 3graine.
Evidence-Based Formulation
cGMP Certified Facility
Non-GMO
Gluten Free
Vegan
Frequently asked questions:
The daily dose is 3 capsules, which can be taken all at once or split throughout the day. If you are sensitive to supplements or medication, you may start with 1-2 capsules per day and gradually increase to 3 capsules over a few weeks.
We recommend taking 3graine with food to help reduce the side effects of loose stool and diarrhea.
Like many other supplements, 3graine may have side effects. The main side effects include changes in urine colour, loose stool, and diarrhea. Research studies have shown that if you experience loose stool or diarrhea, it will likely improve after a few weeks of continuous use. If side effects persist, we recommend discontinuing use.
One bottle will last one month if you take 3 capsules per day.
Most people who benefit will begin to see a response around 2-3 months of consistent use.